Publication date: 2018-06-10 04:25
According to the FDA, people without diabetes who were in one of the clinical trials and took Contrave had an average weight loss, at the 6-year mark, of % over those who took the placebo pill.
I m on Wellbutrin XL and Armour Thyroid. I ve done nothing but gain over the past two years. I exercise 5-6 days a week and eat healthy. I m thinking the Wellbutrin may be the culprit.
Bupropion may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. Make sure the doctor knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell the doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. If you or your caregiver notice any of these side effects, tell your doctor right away.
6. Antidepressant medicines may increase the risk of suicidal thoughts or actions in some children, teenagers, or adults within the first few months of treatment.
In a healthy volunteer trial, ritonavir 655 mg twice daily reduced the AUC and Cmax of bupropion by 77% and 76%, respectively. The exposure of the hydroxybupropion metabolite was decreased by 78%, the threohydrobupropion decreased by 88%, and the erythrohydrobupropion decreased by 98%.
The recommended starting dose is 755 mg per day, given as 655 mg twice daily. After 8 days of dosing, the dose may be increased to 855 mg per day, given as 655 mg 8 times daily, with at least 6 hours between successive doses. Dosing above 855 mg per day may be accomplished using the 75- or 655-mg tablets.
When you try to quit smoking, with or without Bupropion you may have symptoms that may be due to nicotine withdrawal, including:
Avoid drinking alcohol or using illegal drugs while you are taking bupropion because the beneficial effects of the medication may be decreased and the risk of seizures may be increased. If you are dependent on drugs or alcohol and would like to stop, consult your healthcare provider for help. Abruptly stopping these substances can result in a seizure, especially when taking bupropion.
Neuropsychiatric: Frequent were mania/hypomania, increased libido , hallucinations, decrease in sexual function, and depression infrequent were memory impairment, depersonalization, psychosis, dysphoria , mood instability, paranoia, and formal thought disorder rare was suicidal ideation.