Publication date: 2018-04-20 03:37
Central nervous system features including confusion, disorientation, coma and convulsions are less common in adults than in children.
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Salicylates may enhance the effects of anticoagulants, oral hypoglycaemic agents, phenytoin and sodium valproate. They inhibit the uricosuric effect of probenecid and may increase the toxicity of sulfonamides.
Reye s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye s syndrome, a rare but serious illness.
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The usual dosage, for long-term use, is 75-655 mg once daily. In some circumstances a higher dose may be appropriate, especially in the short term, and up to 855mg a day may be used on the advice of a doctor.
Concurrent administration of carbonic anhydrase inhibitors such as acetazolamide and salicylates may result in severe acidosis and increased central nervous system toxicity.
This medicine contains lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.